Sertraline — Drug Interactions, Alcohol & Pregnancy Guide

Last reviewed: · Source: US FDA drug label database

About Sertraline

Sertraline is one of the most commonly prescribed antidepressants in the UK. It is an SSRI used for depression, anxiety, OCD, and PTSD. It takes 4-6 weeks to reach full effect and should not be stopped suddenly.

Also sold as: Zoloft, Lustral

Drug class SSRI (Selective Serotonin Reuptake Inhibitor)
Used for Depression, Anxiety, OCD, PTSD, Panic disorder
Max adult dose 50-200mg once daily
OTC in UK Prescription only

Sertraline and Alcohol

🟡 USE WITH CAUTION

Avoid alcohol with sertraline — it can worsen depression, cause sedation, and unpredictably affect your mood.

Full guide →

Sertraline in Pregnancy

🟡 USE WITH CAUTION

Sertraline in pregnancy requires careful assessment of risks vs benefits — stopping antidepressants without medical advice is often more harmful than continuing.

Full guide →

Sertraline — Drug Combinations

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Not sure if Sertraline is safe with your other medications?

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