Can You Take Co-Amoxiclav with Alcohol?
Last reviewed: · Source: US FDA drug label database
Avoid alcohol with co-amoxiclav — alcohol impairs your immune system and may worsen GI side effects, which are already common with this antibiotic.
Is it safe to take Co-Amoxiclav with Alcohol?
Co-amoxiclav (Augmentin) is a combination antibiotic (amoxicillin + clavulanic acid) used for more resistant infections. GI side effects (nausea, diarrhoea, stomach cramps) are particularly common with co-amoxiclav. Alcohol worsens these side effects and impairs the immune response. While there is no dangerous direct interaction, drinking alcohol while fighting a serious infection is generally counterproductive.
How do Co-Amoxiclav and Alcohol interact?
No significant pharmacokinetic interaction between co-amoxiclav and alcohol. The clavulanic acid component is metabolised hepatically and alcohol may mildly affect this, but the main concerns are pharmacodynamic (worsened GI effects) and immunological (alcohol-induced immune impairment).
Data sourced from the US Food and Drug Administration (FDA) drug label database: OpenFDA co-amoxiclav drug label.
Who should be careful?
Anyone taking co-amoxiclav — particularly those already experiencing GI side effects.
What if I've already taken Co-Amoxiclav and Alcohol?
No immediate medical concern. Probiotics may help with GI side effects. Complete the full antibiotic course.
Not sure if this combination is safe for your specific situation?
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Frequently Asked Questions
Can I drink on Augmentin?
Best avoided. Augmentin already commonly causes nausea and diarrhoea, and alcohol will worsen these side effects and impair your recovery.
Is it safe to drink on co-amoxiclav?
There is no dangerous direct interaction, but alcohol impairs immunity, worsens GI side effects, and counteracts your body's fight against infection.
How long after co-amoxiclav can I drink?
Once you have finished your course and feel well, there is no specific waiting period required. Wait until you feel recovered from your illness.
Can co-amoxiclav and alcohol cause diarrhoea?
Co-amoxiclav alone frequently causes diarrhoea. Alcohol can worsen gut flora disruption and GI upset, making this more likely.